Frank L. VanderSloot (born August 14, 1948) is an American entrepreneur, radio network owner, rancher, and political campaign financier. He is the founder and chief executive officer of Melaleuca, Inc. His other business interests include Riverbend Ranchand Riverbend Communications. VanderSloot also serves on the board of directors and executive board of the U.S. Chamber of Commerce.

In 2011, the Land Report listed him as the nation’s 92nd largest landowner。In 1985, VanderSloot founded Melaleuca, Inc.A multi-level marketing company that sells nutritional supplements, cleaning supplies, and personal-care products,and he has been president and chief executive officer ever since. Melaleuca operates internationally, with U.S. operations centered in Idaho Falls, Idaho, and Knoxville, Tennessee. "Independent marketing executives" receive commissions from Melaleuca for each purchase made by people they refer, and from sales made by their customers and by people their customers refer, through seven "referral generations"; customers buy directly from Melaleuca's website or retail locations The company refers to this arrangement as “Consumer Direct Marketing," a term it has trademarked. Half of the legacy distributors from Oil of Melaleuca left after the new company was formed.