A boy whose last wish was to be home for his favourite holiday has died, two weeks after his hometown welcomed him with a Christmas tree outside his window and a motorcycle-riding Santa Claus.

Doctors had told the family of 13-year-old Devin Kohlman that he didn't have long to live, so residents in the city of Port Clinton, Ohio spent the past few weeks giving him an early Christmas.

They sang carols outside the family's apartment, piled tonnes of shaved ice into drifting snow near his window and decorated a park with colourful strings of Christmas lights, reindeer cutouts and a red "Merry Christmas, Devin" sign.

Devin, who was diagnosed with brain cancer in the summer of 2012, died on Monday afternoon, said family friend Roseann Hickman.

Family and friends gathered for a vigil after his death while an early-season snow fell over the city.

Devin was flown home from Cincinnati, where he was being treated, on October 27 so that he could spend his final days at home. Residents filled the city's main street late at night as Devin was driven home with a police escort.

While he couldn't go outside, he could see from a window how the community was helping his last wish come true.

Hundreds of people, some in Santa hats, sang Christmas carols after his return and Santa himself showed up on a motorcycle.

"It brought him a sense of joy to know so many people cared," Ms Hickman said.

Thousands of cards from as far away as France and Ireland filled the family's apartment. They had been sent by people who had heard his story, Ms Hickman said.

"Their entire apartment is covered in cards, all over the wall," she said. "I can't even begin to fathom the number."

Toys and teddy bears were sent too. Donation boxes were set up all over the city of about 6000 people, which sits about midway between Toledo and Cleveland.

Devin gave away many of the gifts, making sure his classmates who came to visit took home a stuffed bear, Ms Hickman said.

"He touched a lot of people," Ms Hickman said. "I hope our community continues to show the love for each other."