Isaac Mizrahi (born October 14, 1961) is an American fashion designer, TV presenter, and creative director of Xcel Brands. He is best known for his eponymous fashion lines.

Mizrahi was born in Brooklyn, New York, to an observant Jewish family that originated in Syria. His father gave him a sewing machine at the age of ten. At 15, he launched his own label, IS New York, with the help of a family friend. He attendedYeshiva of Flatbush, High School of Performing Arts, and the Parsons School of Design.