Although Sabino is only 40 years old, it has a rich sports tradition, mainly in the sport of football. Apart from football Sabino has also won team state championships in cheerleading (2004, 2010) golf (1986), baseball (1997), men's (1995, 2005) and women's soccer (1996, 2008), swimming and diving, cross country (2007), and track and field, and individual state titles in wrestlingand tennis.

Sabino has garnered a reputation in the local marching band community for fielding highly entertaining productions which showcase intriguing musical repertoire and a high level of energetic musicality in the areas of percussion, winds, and color guard (flag spinning). Through the years, the band has consistently been considered by fans, teachers, and instructors, as one of the premiere bands in Tucson and in the state of Arizona. The band has regularly won state titles and often travels out of Arizona to compete with the top bands from around the country.